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Wednesday May 21
Henry G. Kunkel Lecture: Lessons from innate immunity interacting with altered self
John Atkinson, MD
Washington University School of Medicine
Thursday May 22
- I Session: AUTOIMMUNE DISEASE GENETICS: A BURGEONING FRONTIER
Chair: Judith James, MD, PhD
The inheritance of multiple sclerosis susceptibility
George Ebers, MD
University of Oxford
Genetics of rheumatoid arthritis: Cracking the code for clues to pathogenesis
Peter K. Gregersen, MD
The Feinstein Institute for Medical Research, North Shore LIJ Health System
Whole genome association studies in Lupus, SLEGEN, etc.
John B. Harley, MD, PhD
Oklahoma Medical Research Foundation
Influence of genetic copy number on autoimmune susceptibility
Robert Kimberly, MD
University of Alabama
BAFF, memory and autoimmunity
Michael P. Cancro, PhD
University of Pennsylvania School of Medicine
Human genetics of infectious diseases: a unified theory
Jean-Laurent Casanova, MD, PhD
Paris Descartes University, Necker-Enfants Malades Hospital & Istitut Pasteur
- II Session: INFLAMMATION
Chairs: Fritz Melchers, PhD and Debra Jeske Zack, MD, PhD
Cytokines in RA: the old, the new and how they all fit together
Jean-Michael Dayer, MD
Geneva School of Medicine
Interleukin-17: A new paradigm in inflammation, autoimmunity and therapy
Sarah L. Gaffen, PhD
University of Buffalo School of Dental Medicine
T-bet: a pro or anti-inflammatory transcription factor?
Laurie Glimcher, MD
Harvard School of Public Health and Harvard Medical School
Inflammatory caspases and inflammasomes: master switches of inflammation
Jürg Tschopp, PhD
University of Lausanne
Lessons learned from anti-CD28
Thomas Hönig, MD
University of Würzburg
Mucosal, B cell and Ig switching interactions in inflammation: How the bacteria supports mucosal immunity
Andrea Cerutti, MD
Weill Medical College of Cornell University
Osteoimmunology: How the immune system signals bone loss in rheumatic disease
Georg Schett, MD
University of Erlangen-Nuremberg
Friday May 23
- III Session: THE MOLECULAR AND CELLULAR BASIS OF (HUMAN) AUTOIMMUNITY
Chair: Robert Carter, MD
Complement, antigen presentation and autoimmunity
Michael C. Carroll, PhD
Harvard Medical School
Targeting BAFF and/or APRIL
Anne Davidson, MD
The Feinstein Institute for Medical Research
Cytokine, chemokine and cellular pathway targets in autoimmunity
Lawrence Steinman, MD
Stanford University School of Medicine
TH17 cells and inflammatory autoimmunity
Vijay K. Kuchroo, MD, PhD
Brigham and Women's Hospital
TLRs, interferons and other genes in autoimmunity
Argyrios Theofilopoulos, MD
Scripps Research Institute
Cellular versus antibody-mediated pathogenesis
Jonathan Edwards, MD
University College London
B cells homeostasis in SLE
Iñaki Sanz, MD
University of Rochester Medical Center
- IV Session: EARLY STEPS OF B CELL DIFFERENTIATION AND THE ORIGIN OF ACUTE LYMPHOBLASTIC LEUKEMIAS
Chair: Vito Pistoia, MD
Early B differentation
Paul Kincade, PhD
Oklahoma Medical Research Foundation
Genetic lesions in ALL
James R. Downing, MD
St. Jude's Children's Research Hospital
High affinity human monoclonal antibodies after influenza booster immunization
Patrick C. Wilson, PhD
Oklahoma Medical Research Foundation
Molecular genetics of DLCL
Riccardo Dalla-Favera, MD
Columbia University
Clinical impact of molecular classification of DLCL
Margaret A. Shipp, MD
Dana Farber Cancer Institute
Saturday May 24
VI Session: ANTIGEN-DRIVEN LYMPHOPROLIFERATIVE DISORDERS
Chair: J. Donald Capra, MD
Infection-associated lymphomas
Marc Lecuit, MD, PhD
Univesity of Paris René Descartes, Necker-Enfants Hospital & Institut Pasteur
B-CLL as an antigen driven process
Nicholas Chiorazzi, MD
The Feinstein Institute for Medical Research
Multisteps-pathogenesis of B-CLL
Carlo M. Croce, MD
Ohio State University Comprehensive Cancer Center
Monoclonal antibody therapy
John Byrd, MD
Ohio State University Medical Center
Antisense oligonucleotide therapy
Asher Alban Chanan-Khan, MD
Roswell Park Cancer Institute
Therapy with proteasome inhibitors
Nikhil Munshi, MD
Dana Farber Cancer Institute
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